Get my NEW BOOK - "Kevin and Indira's Guide to Getting Into Medical School" at www.lulu.com Contact me at kgahern@davincipress.com Download my new free biochemistry book at biochem.science.oregonstate.edu Check out all of my course videos at www.youtube.com Check out all of my workshops at www.youtube.com Check out my Metabolic Melodies at www.davincipress.com My courses can be taken for credit (wherever you live) via OSU's ecampus. For details, see ecampus.oregonstate.edu Check out my free iTunes courses for your iPad or iPhone Biochemistry for Pre-Meds - itunesu.itunes.apple.com Elementary Biochemistry - itunesu.itunes.apple.com Kevin & Indira's Guide to Getting Into Medical School - itunes.apple.com Highlights Translation 3 1. Post-translational processing of proteins gives them their final structure and properties. One such modification was discussed for insulin. This involves proteolytic cleavage at two places in the insulin precursor, giving rise to a final structure that has two chains held together by disulfide bonds. 2. Proteins do not have long lifetimes in the cell. They are broken down in cells in cellular structures called proteasomes. Proteins targeted for degradation are tagged with the peptide known as ubiquitin. 3. Selenocysteine is a rare amino acid occasionally incorporated into proteins. It is sometimes called the 21st amino acid. It is because of this that trace amounts of selenium are needed in the diet. 4. Proper folding of proteins is important. A ...
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